Preheat your oven to 425°F (220°C). Line a baking sheet with parchment paper and set aside.
In a mixing bowl, whisk together the flour, baking powder, baking soda, salt, and sugar.
Add the cold butter cubes to the flour mixture. Using a pastry cutter or a fork, cut the butter into the flour until the mixture resembles coarse crumbs.
In another bowl, combine buttermilk and vanilla extract. Gradually pour the buttermilk mixture into the flour mixture, stirring gently until just combined.
Fold in the blueberries, being careful not to overmix the dough.
Turn the dough out onto a lightly floured surface. Gently pat the dough into a rectangle about 1 inch thick. Fold the dough over itself a couple of times to create layers.
Cut out biscuits using a biscuit cutter or a glass. Place them on the prepared baking sheet, leaving some space between each biscuit.
Bake in the preheated oven for 12-15 minutes, or until the biscuits are golden brown on top.
Remove from the oven and allow to cool slightly before serving.