Preheat your oven to 425°F (220°C). Line a sheet pan with parchment paper for easier cleanup (optional).
Wash and prepare the vegetables. Slice the zucchini into half-moons, chop the bell pepper into bite-sized pieces, cut the red onion into wedges, and trim the broccoli into florets.
In a large mixing bowl, combine the prepared vegetables and cherry tomatoes.
Drizzle the olive oil over the veggies, then sprinkle with garlic powder, dried oregano, salt, and black pepper.
Toss everything together with a rubber spatula or spoon until the vegetables are evenly coated.
Spread the vegetables out in a single layer on the prepared sheet pan.
Roast in the preheated oven for about 25 minutes, or until the vegetables are tender and slightly charred, stirring halfway through for even cooking.
Remove from the oven and let cool for a few minutes before serving.
For added flavor, consider topping with fresh herbs like parsley or basil before serving.