Cook the penne pasta according to package instructions in a large pot of salted boiling water. Drain and set aside.
In a frying pan, heat olive oil over medium-high heat. Add the sliced beef and cook until browned, about 3-4 minutes. Remove the beef from the pan and set aside.
In the same pan, add the sliced onion and bell peppers. Sauté until softened, about 5 minutes. Add minced garlic, salt, black pepper, and Worcestershire sauce; cook for an additional minute.
Reduce the heat to medium and stir in the softened cream cheese until melted and smooth.
Gradually add the beef broth, stirring until well combined and the sauce is creamy.
Return the cooked beef to the pan, then add the drained pasta. Mix everything together until well coated with the sauce.
Sprinkle shredded provolone cheese over the top, cover, and let it sit for a few minutes until the cheese melts.
Serve hot, garnished with additional black pepper if desired.